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Ingredient Knowledge

Explore evidence-based skincare ingredient information through the lens of skin barrier science and formulation context.

Humectant

1,2-Hexanediol

1,2-Hexanediol

A humectant and preservation-support ingredient used for formula stability.

Functional evidenceCompatible

Active ingredient

3-O-Ethyl Ascorbic Acid

Vitamin C Derivative

A vitamin C derivative used to support radiance and uneven tone.

Moderate evidenceCompatible

Active ingredient

Acetyl Dipeptide-1 Cetyl Ester

Peptide

A lipopeptide used to support comfort and visible skin calm.

Strong evidenceBarrier supportive

Active ingredient

Acetyl Hexapeptide-8

Argireline

A peptide used to soften the look of expression lines.

Moderate evidenceCompatible

Supportive

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

A stabilizing polymer that builds texture and supports emulsion structure.

Functional evidenceCompatible

active

Adapalene

Adapalene

Adapalene is an active skincare ingredient used as a retinoid commonly used for acne-prone skin and visible pore congestion. It is especially relevant for acne-prone skin and comedonal breakouts.

Strong evidenceBarrier caution

Active ingredient

Adenosine

Adenosine

A skin-conditioning ingredient used to support smoother-looking skin.

Strong evidenceBarrier supportive

Supportive

Alanine

Alanine

An amino acid that contributes to skin conditioning and moisture support.

Limited evidenceBarrier supportive

Supportive

Allantoin

Allantoin

A calming supportive ingredient that helps comfort skin prone to dryness or visible irritation.

Moderate evidenceStrongly supportive

Humectant

Aloe Barbadensis Leaf Juice

Aloe Vera Juice

A water-rich botanical juice used to hydrate and soothe the feel of skin.

Moderate evidenceBarrier supportive

supportive

Aloe Vera

Aloe barbadensis leaf juice

Aloe Vera is a supportive skincare ingredient used to help hydrate and comfort the feel of dry, stressed, or sun-exposed skin. It is especially relevant for temporary comfort, lightweight hydration, and sensitive skin support.

Moderate evidenceBarrier supportive

Active ingredient

Alpha-Arbutin

Alpha-Arbutin

A purified arbutin form used to support a more even-looking complexion.

Strong evidenceCompatible

Active ingredient

Alpha-Lipoic Acid

Alpha-Lipoic Acid

An antioxidant used to support skin against visible oxidative stress.

Moderate evidenceUse With Care

Supportive

Alteromonas Ferment Extract

Alteromonas Ferment Extract

A marine ferment extract used to support hydration and environmental resilience.

Limited evidenceBarrier supportive

Supportive

Althaea Officinalis Root Extract

Marshmallow Root Extract

Marshmallow root extract used to soften and comfort dry-feeling skin.

Limited evidenceBarrier supportive

Active ingredient

Aminopropyl Ascorbyl Phosphate

Vitamin C Derivative

A vitamin C derivative used to support brightness and visible tone clarity.

Strong evidenceCompatible

Emollient

Amodimethicone

Amodimethicone

A conditioning silicone used to improve smoothness and cosmetic elegance.

Functional evidenceCompatible

Humectant

Anhydroxylitol

Anhydroxylitol

A sugar-derived humectant used in moisture-supporting complexes.

Moderate evidenceStrongly supportive

Active ingredient

Apigenin

Apigenin

A flavonoid used in formulas focused on visible calm and antioxidant support.

Limited evidenceBarrier supportive

Supportive

Aqua

Water

Water, the primary solvent and base for many hydrating skincare formulas.

Functional evidenceCompatible

Active ingredient

Arbutin

Arbutin

A tone-supporting ingredient used to improve the look of uneven pigmentation.

Strong evidenceCompatible

Active ingredient

Arctostaphylos Uva Ursi Leaf Extract

Bearberry Extract

Bearberry extract used in tone-supporting cosmetic formulas.

Limited evidenceCompatible

Emollient

Argania Spinosa Kernel Oil

Argan Oil

Argan oil, an emollient oil that supports softness and skin conditioning.

Limited evidenceBarrier supportive

Supportive

Arginine

Arginine

An amino acid used for skin conditioning and formula pH support.

Moderate evidenceBarrier supportive

Supportive

Artemisia Princeps Leaf Extract

Mugwort Extract

Mugwort extract used to support the appearance of calm, balanced skin.

Limited evidenceBarrier supportive

Supportive

Ascophyllum Nodosum Extract

Brown Algae Extract

Brown algae extract used for hydration and skin-conditioning benefits.

Limited evidenceBarrier supportive

Active ingredient

Ascorbic Acid

Vitamin C

Pure vitamin C, used for antioxidant support, radiance, and visible tone refinement.

Strong evidenceUse With Care

Active ingredient

Ascorbyl Glucoside

Vitamin C Derivative

A vitamin C derivative used to support radiance with improved formula stability.

Moderate evidenceCompatible

Active ingredient

Asiatic Acid

Asiatic Acid

A centella component associated with supportive care for stressed-looking skin.

Limited evidenceBarrier supportive

Active ingredient

Asiaticoside

Asiaticoside

A centella-derived compound used in formulas focused on skin comfort and recovery.

Moderate evidenceBarrier supportive

Supportive

Aspartic Acid

Aspartic Acid

An amino acid used in skin-conditioning and moisture-supportive formulas.

Limited evidenceBarrier supportive

Active ingredient

Astaxanthin

Astaxanthin

A carotenoid antioxidant used to support radiance and environmental resilience.

Moderate evidenceBarrier supportive

Supportive

Avena Sativa Bran Extract

Oat Bran Extract

Oat bran extract used for soothing and skin-conditioning benefits.

Moderate evidenceBarrier supportive

Supportive

Avena Sativa Kernel Extract

Oat Extract

Oat extract used to calm and condition sensitive-feeling skin.

Moderate evidenceStrongly supportive

Active ingredient

Avena Sativa Kernel Flour

Oat Flour

Oat flour used to soothe, soften, and support dry-feeling skin.

Strong evidenceStrongly supportive

Emollient

Avena Sativa Kernel Oil

Oat Oil

Oat oil, a lipid-rich emollient used to support barrier comfort.

Moderate evidenceStrongly supportive

Supportive

Avena Sativa Peptide

Oat Peptide

Oat-derived peptides used to support skin conditioning and softness.

Limited evidenceBarrier supportive

Active ingredient

Azelaic Acid

Azelaic Acid

A multi-benefit acid used to support clarity, redness-prone skin, and uneven tone.

Strong evidenceBarrier supportive

Active ingredient

Bakuchiol

Bakuchiol

A plant-derived active used for visible smoothing and tone support in gentle-aging formulas.

Moderate evidenceBarrier supportive

Emollient

Behenyl Alcohol

Behenyl Alcohol

A fatty alcohol that gives formulas body and a velvety finish.

Functional evidenceBarrier supportive

Supportive

Bentonite

Bentonite Clay

A swelling clay used for texture, absorption, and formula body.

Functional evidenceCompatible

Preservative

Benzyl Alcohol

Benzyl Alcohol

A preservative and solvent used in cosmetic formulas.

Strong evidenceCompatible

Supportive

Beta-Glucan

Beta-Glucan

A soothing polysaccharide that supports hydration and helps visibly calm stressed skin.

Moderate evidenceStrongly supportive

Humectant

Betaine

Betaine

An osmolyte humectant that helps skin feel hydrated, soft, and balanced.

Moderate evidenceStrongly supportive

Supportive

Bifida Ferment Lysate

Bifida Ferment Lysate

A ferment lysate used to support skin conditioning and resilience-focused care.

Moderate evidenceBarrier supportive

Humectant

Biosaccharide Gum-1

Biosaccharide Gum-1

A sugar-derived film former used to soothe and support surface hydration.

Moderate evidenceBarrier supportive

Supportive

Bisabolol

Bisabolol

A soothing component commonly associated with chamomile and sensitive-skin comfort.

Moderate evidenceBarrier supportive

Emollient

Borago Officinalis Seed Oil

Borage Oil

Borage oil, a botanical lipid used in dry-skin supportive formulas.

Moderate evidenceBarrier supportive

Humectant

Butylene Glycol

Butylene Glycol

A lightweight humectant and solvent that supports hydration and formula elegance.

Strong evidenceBarrier supportive

Active ingredient

Butylresorcinol

Butylresorcinol

A resorcinol derivative used to support the look of even pigmentation.

Moderate evidenceUse With Care

Emollient

Butyrospermum Parkii Butter

Shea Butter

Shea butter, a rich emollient that helps comfort dry skin.

Moderate evidenceBarrier supportive

Active ingredient

Caffeine

Caffeine

A stimulant-derived ingredient used to support the look of firmness and freshness.

Strong evidenceCompatible

Supportive

Calendula Officinalis Flower Extract

Calendula Extract

A botanical extract traditionally used in formulas for dry or delicate skin comfort.

Limited evidenceBarrier supportive

Emollient

Calophyllum Inophyllum Seed Oil

Tamanu Oil

Tamanu oil, a rich botanical oil used in skin-conditioning formulas.

Limited evidenceCompatible

Emollient

Camellia Oleifera Seed Oil

Camellia Seed Oil

Camellia seed oil, a silky emollient used to soften skin.

Limited evidenceBarrier supportive

Active ingredient

Camellia Sinensis Leaf Extract

Green Tea Extract

A green tea extract rich in antioxidant compounds for environmental skin support.

Moderate evidenceBarrier supportive

Emollient

Cannabis Sativa Seed Oil

Hemp Seed Oil

Hemp seed oil, a lipid-rich emollient used for skin conditioning.

Moderate evidenceBarrier supportive

Emollient

Caprylic/Capric Triglyceride

Caprylic/Capric Triglyceride

A lightweight emollient that softens skin and improves formula glide.

Strong evidenceBarrier supportive

Active ingredient

Capryloyl Salicylic Acid

LHA

A lipophilic salicylic acid derivative used for gentle surface refinement.

Moderate evidenceUse With Care

Humectant

Caprylyl Glycol

Caprylyl Glycol

A humectant and preservative booster that supports skin feel and formula stability.

Moderate evidenceCompatible

Supportive

Carbomer

Carbomer

A gel-forming polymer used to create elegant, stable textures.

Functional evidenceCompatible

Supportive

Carnitine

Carnitine

A conditioning ingredient used in formulas focused on skin balance.

Limited evidenceCompatible

Supportive

Cellulose Gum

Cellulose Gum

A cellulose-derived thickener used to improve texture and stability.

Functional evidenceCompatible

supportive

Centella Asiatica

Cica / gotu kola

Centella Asiatica is a supportive skincare ingredient used to support a calmer-looking complexion and helps comfort sensitive-feeling skin. It is especially relevant for redness-prone, reactive, or stressed skin.

Moderate evidenceBarrier supportive

Supportive

Centella Asiatica Extract

Cica

A botanical extract used to support the look of calm, resilient skin.

Moderate evidenceBarrier supportive

Active ingredient

Ceramide AP

Ceramide

A ceramide used to support barrier integrity and reduce moisture loss.

Strong evidenceStrongly supportive

Active ingredient

Ceramide AS

Ceramide

A ceramide used to support the lipid matrix of the skin barrier.

Strong evidenceStrongly supportive

Active ingredient

Ceramide EOP

Ceramide

A complex ceramide important to barrier structure and moisture retention.

Strong evidenceStrongly supportive

Active ingredient

Ceramide EOS

Ceramide

A ceramide associated with barrier structure and dry-skin support.

Strong evidenceStrongly supportive

Active ingredient

Ceramide NG

Ceramide

A barrier lipid that helps replenish dry, compromised skin.

Strong evidenceStrongly supportive

Active ingredient

Ceramide NP

Ceramide

A skin-identical lipid that helps replenish the barrier and reduce moisture loss.

Strong evidenceStrongly supportive

Active ingredient

Ceramide NS

Ceramide

A ceramide used in formulas designed to reinforce the skin barrier.

Strong evidenceStrongly supportive

supportive

Ceramides

Ceramide NP / AP / EOP

Ceramides are a supportive skincare ingredient used to help replenish the lipid structure that keeps the skin barrier comfortable and resilient. It is especially relevant for dry, sensitive, tight, or barrier-compromised skin.

Strong evidenceBarrier supportive

Emollient

Cetearyl Alcohol

Cetearyl Alcohol

A fatty alcohol blend used to build creamy texture and condition skin.

Functional evidenceBarrier supportive

Emulsifier

Cetearyl Glucoside

Cetearyl Glucoside

A sugar-derived emulsifier used for mild, stable cream systems.

Functional evidenceCompatible

Emulsifier

Cetearyl Olivate

Cetearyl Olivate

An olive-derived emulsifier used for smooth, skin-conditioning creams.

Functional evidenceBarrier supportive

Emollient

Cetyl Alcohol

Cetyl Alcohol

A fatty alcohol that thickens formulas and leaves skin feeling soft.

Functional evidenceBarrier supportive

Supportive

Cetyl Hydroxyethylcellulose

Cetyl Hydroxyethylcellulose

A thickening polymer used to stabilize texture and improve skin feel.

Functional evidenceCompatible

Supportive

Chamomilla Recutita Flower Extract

Chamomile Extract

A chamomile extract used to support the appearance of calm, comfortable skin.

Moderate evidenceBarrier supportive

Supportive

Charcoal Powder

Charcoal Powder

A porous powder used in rinse-off formulas for cleansing and absorption.

Limited evidenceUse With Care

Supportive

Chlorella Vulgaris Extract

Chlorella Extract

A microalgae extract used to support skin vitality and barrier-focused formulas.

Strong evidenceBarrier supportive

Preservative

Chlorphenesin

Chlorphenesin

A preservative used to help protect water-containing formulas.

Strong evidenceCompatible

Active ingredient

Cholesterol

Cholesterol

A skin-identical lipid that works with ceramides and fatty acids to support the barrier.

Strong evidenceStrongly supportive

Active ingredient

Chrysin

Chrysin

A flavonoid used in eye-area formulas for the look of clarity and brightness.

Strong evidenceCompatible

Supportive

Citric Acid

Citric Acid

An alpha hydroxy acid commonly used to adjust formula pH.

Functional evidenceCompatible

Supportive

Citrullus Lanatus Fruit Extract

Watermelon Extract

Watermelon extract used for hydration and antioxidant support.

Limited evidenceBarrier supportive

Emollient

Coco-Caprylate/Caprate

Coco-Caprylate/Caprate

A lightweight emollient used as a silky alternative to heavier oils.

Functional evidenceBarrier supportive

Emollient

Cocos Nucifera Oil

Coconut Oil

Coconut oil, a rich emollient that softens and reduces surface dryness.

Moderate evidenceCompatible

active

Coenzyme Q10

Ubiquinone

Coenzyme Q10 is an active skincare ingredient used to support antioxidant care and helps skin look more energized and resilient. It is especially relevant for dullness, visible fatigue, and early aging concerns.

Moderate evidenceBarrier neutral

humectant

Collagen

Hydrolyzed collagen

Collagen is a humectant skincare ingredient used to help skin feel hydrated and smooth on the surface through film-forming moisture support. It is especially relevant for temporary plumping, softness, and dry surface texture.

Limited evidenceBarrier supportive

Active ingredient

Colloidal Oatmeal

Colloidal Oatmeal

A finely milled oat ingredient known for soothing dry, sensitive, and itchy-feeling skin.

Strong evidenceStrongly supportive

active

Copper Peptides

GHK-Cu / copper tripeptide-1

Copper Peptides are an active skincare ingredient used to support the look of firmness, recovery, and overall skin resilience. It is especially relevant for aging concerns, visible fatigue, and supportive repair-focused routines.

Moderate evidenceBarrier supportive

Active ingredient

Copper Tripeptide-1

Copper Peptide

A copper peptide used to support repair-oriented skin conditioning and firmness.

Moderate evidenceBarrier supportive

Active ingredient

Creatine

Creatine

An energy-associated molecule used to support healthy-looking skin.

Moderate evidenceBarrier supportive

Supportive

Cucumis Sativus Fruit Extract

Cucumber Extract

Cucumber extract used for lightweight hydration and a fresh skin feel.

Limited evidenceBarrier supportive

Active ingredient

Curcuma Longa Root Extract

Turmeric Extract

Turmeric extract used for antioxidant support and visible skin calm.

Limited evidenceBarrier supportive

Emollient

Cyclohexasiloxane

Cyclohexasiloxane

A volatile silicone used to improve spread and reduce tackiness.

Functional evidenceCompatible

Emollient

Cyclopentasiloxane

Cyclopentasiloxane

A volatile silicone that gives formulas a light, silky finish.

Functional evidenceCompatible

Preservative

Dehydroacetic Acid

Dehydroacetic Acid

A preservative used to support formula protection and shelf stability.

Strong evidenceCompatible

Emollient

Dicaprylyl Carbonate

Dicaprylyl Carbonate

A dry-touch emollient that improves spread and softness.

Functional evidenceBarrier supportive

Humectant

Diglycerin

Diglycerin

A gentle humectant that supports lasting hydration and skin softness.

Moderate evidenceStrongly supportive

Emollient

Dimethicone

Dimethicone

A silicone emollient that helps smooth skin and reduce moisture loss.

Strong evidenceStrongly supportive

Active ingredient

Dioic Acid

Dioic Acid

A dicarboxylic acid used in formulas for tone and clarity support.

Limited evidenceCompatible

Active ingredient

Diosmin

Diosmin

A flavonoid used in cosmetic formulas for skin-conditioning support.

Limited evidenceCompatible

Active ingredient

Dipeptide-2

Dipeptide-2

A peptide used in eye-area formulas for conditioning and visible freshness.

Moderate evidenceCompatible

Supportive

Dipotassium Glycyrrhizate

Licorice Derivative

A licorice-derived salt used for soothing and visible redness support.

Moderate evidenceBarrier supportive

Supportive

Disodium EDTA

Disodium EDTA

A chelating agent that supports formula stability and preservative performance.

Functional evidenceCompatible

Active ingredient

Ectoin

Ectoin

A stress-protection molecule used to help support hydration and environmental resilience.

Moderate evidenceStrongly supportive

Active ingredient

Ergothioneine

Ergothioneine

An antioxidant amino acid derivative used for environmental protection support.

Moderate evidenceBarrier supportive

Active ingredient

Escin

Escin

A horse chestnut-derived compound used to support the look of toned skin.

Limited evidenceCompatible

Emollient

Ethylhexyl Palmitate

Ethylhexyl Palmitate

An emollient ester used to soften skin and improve formula glide.

Functional evidenceCompatible

Preservative

Ethylhexylglycerin

Ethylhexylglycerin

A preservative booster and skin-conditioning ingredient used for formula protection.

Strong evidenceCompatible

Active ingredient

Ferulic Acid

Ferulic Acid

An antioxidant often paired with vitamins C and E for environmental support.

Moderate evidenceBarrier supportive

Supportive

Fucus Vesiculosus Extract

Bladderwrack Extract

Bladderwrack extract used for skin conditioning and marine-derived support.

Limited evidenceBarrier supportive

Supportive

Galactomyces Ferment Filtrate

Galactomyces Ferment Filtrate

A ferment filtrate used to support radiance, hydration, and skin conditioning.

Moderate evidenceBarrier supportive

Active ingredient

Ganoderma Lucidum Extract

Reishi Mushroom Extract

Reishi mushroom extract used for antioxidant and skin-conditioning support.

Limited evidenceBarrier supportive

Active ingredient

Genistein

Genistein

A soy-derived isoflavone used for antioxidant and skin-conditioning support.

Limited evidenceBarrier supportive

Supportive

Glucomannan

Glucomannan

A plant-derived polysaccharide used for texture, hydration, and skin feel.

Functional evidenceBarrier supportive

Active ingredient

Gluconolactone

PHA

A polyhydroxy acid that supports mild exfoliation with added humectant properties.

Moderate evidenceBarrier supportive

Supportive

Glutamic Acid

Glutamic Acid

An amino acid used to support hydration, conditioning, and skin comfort.

Limited evidenceBarrier supportive

Supportive

Glutamine

Glutamine

An amino acid used in formulas focused on hydration and skin support.

Limited evidenceBarrier supportive

Active ingredient

Glutathione

Glutathione

An antioxidant used to support tone and environmental skin defense.

Moderate evidenceBarrier supportive

Humectant

Glycerin

Glycerin

A classic humectant that draws water into the skin for soft, steady hydration.

Strong evidenceStrongly supportive

Emulsifier

Glyceryl Stearate

Glyceryl Stearate

An emulsifier and emollient that helps build creamy, stable textures.

Functional evidenceBarrier supportive

Supportive

Glycine

Glycine

A small amino acid used to support hydration and skin conditioning.

Moderate evidenceBarrier supportive

Active ingredient

Glycolic Acid

Glycolic Acid

A small alpha hydroxy acid that supports surface renewal and smoother-looking skin.

Strong evidenceUse With Care

Active ingredient

Glycyrrhiza Glabra Root Extract

Licorice Root Extract

A licorice root extract used to support visible calm and a more even-looking tone.

Moderate evidenceBarrier supportive

supportive

Green Tea Extract

Camellia sinensis extract

Green Tea Extract is a supportive skincare ingredient used to offer antioxidant support and helps calm the look of stressed skin. It is especially relevant for redness-prone, oily, or environmentally stressed skin.

Moderate evidenceBarrier supportive

Active ingredient

Haematococcus Pluvialis Extract

Red Algae Extract

A microalgae extract known as a natural source of astaxanthin.

Limited evidenceBarrier supportive

Supportive

Hamamelis Virginiana Water

Witch Hazel Water

Witch hazel water, an astringent botanical distillate used for toning formulas.

Moderate evidenceUse With Care

Emollient

Helianthus Annuus Seed Oil

Sunflower Seed Oil

Sunflower seed oil, rich in skin-conditioning lipids for barrier support.

Moderate evidenceStrongly supportive

Emollient

Hemisqualane

Hemisqualane

A lightweight emollient that gives slip and softness with a clean finish.

Moderate evidenceBarrier supportive

Active ingredient

Hesperidin Methyl Chalcone

Hesperidin Methyl Chalcone

A flavonoid derivative used in eye-area formulas for visible tone support.

Moderate evidenceCompatible

Active ingredient

Hexylresorcinol

Hexylresorcinol

A brightening-support ingredient used for the appearance of more even skin.

Moderate evidenceUse With Care

Emollient

Hippophae Rhamnoides Fruit Oil

Sea Buckthorn Oil

Sea buckthorn oil, a carotenoid-rich oil used for conditioning and radiance.

Limited evidenceBarrier supportive

Supportive

Histidine

Histidine

An amino acid associated with skin conditioning and natural moisturizing factors.

Limited evidenceBarrier supportive

Humectant

Honey Extract

Honey Extract

A humectant botanical-derived ingredient used to soften and condition skin.

Moderate evidenceBarrier supportive

Supportive

Houttuynia Cordata Extract

Heartleaf Extract

Heartleaf extract used in formulas for visibly calm, balanced skin.

Limited evidenceBarrier supportive

Humectant

Hyaluronic Acid

Hyaluronic Acid

A water-binding molecule used to hydrate and visibly plump the skin surface.

Strong evidenceStrongly supportive

Emulsifier

Hydrogenated Lecithin

Hydrogenated Lecithin

A stabilized lecithin form used for barrier-supportive texture and delivery.

Moderate evidenceBarrier supportive

Emollient

Hydrogenated Polyisobutene

Hydrogenated Polyisobutene

A cushiony emollient that helps soften skin and improve glide.

Functional evidenceBarrier supportive

Humectant

Hydrolyzed Glycosaminoglycans

Hydrolyzed Glycosaminoglycans

Skin-conditioning polysaccharides used to support hydration and surface smoothness.

Moderate evidenceBarrier supportive

Humectant

Hydrolyzed Hyaluronic Acid

Hydrolyzed Hyaluronic Acid

A lower-molecular-weight hyaluronic acid form used for layered hydration.

Moderate evidenceStrongly supportive

Supportive

Hydrolyzed Rice Protein

Hydrolyzed Rice Protein

A rice-derived protein used to support skin conditioning and softness.

Limited evidenceBarrier supportive

Humectant

Hydrolyzed Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid

A hydrolyzed hyaluronic acid salt used for lightweight moisture support.

Moderate evidenceStrongly supportive

Supportive

Hydrolyzed Yeast Extract

Hydrolyzed Yeast Extract

A yeast-derived ingredient used to support hydration and overall skin conditioning.

Strong evidenceBarrier supportive

Humectant

Hydroxyethyl Urea

Hydroxyethyl Urea

A humectant that helps improve skin hydration and a soft after-feel.

Moderate evidenceStrongly supportive

Supportive

Hydroxyethylcellulose

Hydroxyethylcellulose

A cellulose-derived thickener that creates smooth, water-based textures.

Functional evidenceCompatible

Supportive

Hydroxyproline

Hydroxyproline

An amino acid derivative used in formulas focused on skin conditioning.

Limited evidenceBarrier supportive

Supportive

Hydroxypropyl Methylcellulose

Hydroxypropyl Methylcellulose

A cellulose-derived polymer used to thicken and stabilize cosmetic formulas.

Functional evidenceCompatible

Humectant

Hydroxypropyltrimonium Hyaluronate

Hyaluronic Acid Derivative

A conditioning hyaluronic acid derivative used for a soft, hydrated skin feel.

Limited evidenceBarrier supportive

Active ingredient

Idebenone

Idebenone

A synthetic antioxidant used in formulas targeting environmental stress.

Moderate evidenceCompatible

Active ingredient

Inonotus Obliquus Extract

Chaga Mushroom Extract

Chaga mushroom extract used for antioxidant and skin-conditioning benefits.

Limited evidenceBarrier supportive

Humectant

Inositol

Inositol

A sugar alcohol used to support skin conditioning and hydration balance.

Limited evidenceBarrier supportive

Emollient

Isoamyl Laurate

Isoamyl Laurate

A biodegradable emollient used for smoothness and a light skin feel.

Functional evidenceBarrier supportive

Active ingredient

Isobutylamido Thiazolyl Resorcinol

Thiamidol

A tone-supporting active used in formulas targeting visible dark spots.

Strong evidenceUse With Care

Emollient

Isododecane

Isododecane

A lightweight emollient solvent used for a dry, elegant finish.

Functional evidenceCompatible

Supportive

Isoleucine

Isoleucine

An amino acid used to support skin conditioning and barrier-oriented care.

Limited evidenceBarrier supportive

emollient

Jojoba Oil

Simmondsia chinensis seed oil

Jojoba Oil is an emollient skincare ingredient used to condition and softens the skin with a lightweight, skin-compatible lipid feel. It is especially relevant for dryness, roughness, and barrier-supportive emollience.

Moderate evidenceBarrier supportive

Supportive

Kaolin

Kaolin Clay

A clay used to absorb excess oil and create a soft, refined finish.

Functional evidenceCompatible

Active ingredient

Kojic Acid

Kojic Acid

A brightening active used in formulas targeting the appearance of dark spots.

Moderate evidenceUse With Care

Active ingredient

Lactic Acid

Lactic Acid

A gentle alpha hydroxy acid that supports exfoliation while also contributing humectant benefits.

Strong evidenceUse With Care

Supportive

Lactobacillus Ferment

Lactobacillus Ferment

A ferment-derived ingredient used for skin-conditioning and microbiome-inspired formulas.

Limited evidenceBarrier supportive

Active ingredient

Lactobionic Acid

PHA

A polyhydroxy acid that gently refines while helping support hydration and softness.

Moderate evidenceBarrier supportive

Supportive

Laminaria Digitata Extract

Kelp Extract

A kelp extract used to support hydration and mineral-rich skin conditioning.

Limited evidenceBarrier supportive

Emollient

Lauric Acid

Lauric Acid

A fatty acid used in cleansing and emollient systems.

Functional evidenceCompatible

Supportive

Lauroyl Lysine

Lauroyl Lysine

An amino-acid-derived powder used for softness and a refined finish.

Functional evidenceCompatible

Emollient

Lauryl Alcohol

Lauryl Alcohol

A fatty alcohol used in formulas for texture and emollient support.

Functional evidenceCompatible

Emulsifier

Lecithin

Lecithin

A phospholipid-rich ingredient that supports emulsions and skin conditioning.

Moderate evidenceBarrier supportive

Supportive

Leucine

Leucine

An amino acid used to support skin conditioning in hydration-focused formulas.

Limited evidenceBarrier supportive

supportive

Licorice Root Extract

Glycyrrhiza glabra extract

Licorice Root Extract is a supportive skincare ingredient used to help calm the look of redness and supports a more even-looking tone. It is especially relevant for redness-prone skin, dullness, and uneven tone.

Moderate evidenceBarrier supportive

Emollient

Limnanthes Alba Seed Oil

Meadowfoam Seed Oil

Meadowfoam seed oil, a stable emollient that supports a smooth skin feel.

Limited evidenceBarrier supportive

Active ingredient

Linoleic Acid

Linoleic Acid

An essential fatty acid that supports the skin’s lipid barrier.

Strong evidenceStrongly supportive

Emollient

Linolenic Acid

Linolenic Acid

An omega fatty acid used for skin conditioning and barrier support.

Moderate evidenceBarrier supportive

Active ingredient

Luteolin

Luteolin

A flavonoid antioxidant used to support skin conditioning and visible comfort.

Limited evidenceBarrier supportive

Supportive

Lysine

Lysine

An amino acid used to support skin conditioning and formula performance.

Limited evidenceBarrier supportive

Emollient

Macadamia Integrifolia Seed Oil

Macadamia Seed Oil

Macadamia oil, an emollient oil used for softness and skin comfort.

Limited evidenceBarrier supportive

Supportive

Macrocystis Pyrifera Extract

Giant Kelp Extract

Giant kelp extract used to support hydration and softness.

Limited evidenceBarrier supportive

Active ingredient

Madecassic Acid

Madecassic Acid

A centella component used in calming formulas for visibly reactive skin.

Limited evidenceBarrier supportive

Active ingredient

Madecassoside

Madecassoside

A purified centella component used for soothing and visible barrier support.

Moderate evidenceBarrier supportive

Active ingredient

Magnesium Ascorbyl Phosphate

Vitamin C Derivative

A vitamin C derivative used in brightening and antioxidant-focused formulas.

Moderate evidenceCompatible

Active ingredient

Malic Acid

Malic Acid

An alpha hydroxy acid used for gentle surface renewal and smoothing.

Moderate evidenceUse With Care

Active ingredient

Maltobionic Acid

Maltobionic Acid

A polyhydroxy acid used for gentle exfoliation and hydration support.

Moderate evidenceBarrier supportive

Active ingredient

Mandelic Acid

Mandelic Acid

A larger alpha hydroxy acid often chosen for slower, gentler surface exfoliation.

Moderate evidenceUse With Care

Active ingredient

Melaleuca Alternifolia Leaf Oil

Tea Tree Oil

Tea tree oil, an aromatic ingredient used in clarity-focused formulas.

Moderate evidenceUse With Care

Active ingredient

Morus Alba Root Extract

Mulberry Root Extract

Mulberry root extract used to support the appearance of even tone.

Limited evidenceBarrier supportive

Emollient

Myristic Acid

Myristic Acid

A fatty acid used in cosmetic formulas for structure and skin feel.

Functional evidenceCompatible

Emollient

Myristyl Alcohol

Myristyl Alcohol

A fatty alcohol used for texture, structure, and emollience.

Functional evidenceCompatible

Active ingredient

N-Acetyl Glucosamine

N-Acetyl Glucosamine

An amino sugar used to support hydration and the appearance of even tone.

Moderate evidenceBarrier supportive

Active ingredient

N-Prolyl Palmitoyl Tripeptide-56 Acetate

Peptide

A lipopeptide used to support the appearance of firmness and skin structure.

Strong evidenceBarrier supportive

Active ingredient

Niacinamide

Vitamin B3

A multi-functional form of vitamin B3 that supports barrier resilience, tone, and visible skin calm.

Strong evidenceStrongly supportive

Active ingredient

Nonapeptide-1

Peptide

A peptide used in formulas targeting the appearance of uneven tone.

Moderate evidenceCompatible

Emollient

Oenothera Biennis Oil

Evening Primrose Oil

Evening primrose oil, a lipid-rich oil used for skin conditioning.

Moderate evidenceBarrier supportive

Emollient

Olea Europaea Fruit Oil

Olive Oil

Olive oil, a rich emollient used to soften and condition skin.

Moderate evidenceCompatible

Emollient

Oleic Acid

Oleic Acid

A fatty acid used for emollience and formula structure.

Moderate evidenceCompatible

Active ingredient

Oligopeptide-68

Peptide

A peptide used to support visible brightness and tone evenness.

Limited evidenceCompatible

Supportive

Opuntia Ficus-Indica Stem Extract

Prickly Pear Extract

Prickly pear extract used for hydration and skin comfort.

Limited evidenceBarrier supportive

Emollient

Oryza Sativa Bran Oil

Rice Bran Oil

Rice bran oil, an emollient oil used for softness and conditioning.

Limited evidenceBarrier supportive

Supportive

Oryza Sativa Extract

Rice Extract

Rice extract used for skin conditioning and a soft, hydrated feel.

Limited evidenceBarrier supportive

Supportive

Oryza Sativa Water

Rice Water

Rice water used in formulas for hydration and skin-conditioning benefits.

Limited evidenceBarrier supportive

Emollient

Palmitic Acid

Palmitic Acid

A fatty acid used to support texture, structure, and emollience.

Functional evidenceCompatible

Active ingredient

Palmitoyl Pentapeptide-4

Peptide

A signal peptide used to support the look of firmness and smoother skin texture.

Strong evidenceBarrier supportive

Active ingredient

Palmitoyl Tetrapeptide-7

Peptide

A peptide used to support the appearance of calm, smoother-looking skin.

Moderate evidenceBarrier supportive

Active ingredient

Palmitoyl Tripeptide-1

Peptide

A lipophilic peptide used in firming and smoothing cosmetic formulas.

Moderate evidenceBarrier supportive

Active ingredient

Palmitoyl Tripeptide-5

Peptide

A peptide used in formulas targeting visible firmness and texture.

Moderate evidenceBarrier supportive

Active ingredient

Palmitoyl Tripeptide-8

Peptide

A peptide used in formulas focused on visible comfort and skin calm.

Moderate evidenceBarrier supportive

Active ingredient

Panax Ginseng Root Extract

Ginseng Extract

Ginseng extract used to support energized, healthy-looking skin.

Limited evidenceBarrier supportive

Supportive

Panthenol

Pro-Vitamin B5

A pro-vitamin B5 ingredient known for soothing, hydrating, and supporting barrier recovery.

Strong evidenceStrongly supportive

Emulsifier

PEG-100 Stearate

PEG-100 Stearate

An emulsifier used to help oil and water phases form stable creams.

Functional evidenceCompatible

Active ingredient

Pentapeptide-59

Peptide

A peptide used in formulas focused on visible soothing and resilience.

Limited evidenceBarrier supportive

Humectant

Pentylene Glycol

Pentylene Glycol

A humectant and solvent that supports hydration and preservation strategy.

Moderate evidenceBarrier supportive

active

Peptides

Signal peptides / peptide blends

Peptides are an active skincare ingredient used to support firmer-looking, smoother-looking skin by signalling visible repair processes. It is especially relevant for fine lines, loss of firmness, and a weakened-looking skin barrier.

Moderate evidenceBarrier supportive

Emollient

Persea Gratissima Oil

Avocado Oil

Avocado oil, a rich emollient used to soften dry skin.

Limited evidenceBarrier supportive

Emollient

Petrolatum

Petroleum Jelly

A highly effective occlusive that helps protect the barrier and reduce water loss.

Strong evidenceStrongly supportive

Preservative

Phenoxyethanol

Phenoxyethanol

A preservative used to help protect formulas from microbial contamination.

Strong evidenceCompatible

Emollient

Phenyl Trimethicone

Phenyl Trimethicone

A glossy silicone emollient that improves slip and skin feel.

Functional evidenceCompatible

Supportive

Phenylalanine

Phenylalanine

An amino acid used in cosmetic formulas for skin conditioning.

Limited evidenceCompatible

Emollient

Phospholipids

Phospholipids

Lipid molecules used to support skin conditioning and formula structure.

Moderate evidenceBarrier supportive

Supportive

Phytic Acid

Phytic Acid

A chelating antioxidant ingredient used to support formula stability and tone care.

Moderate evidenceCompatible

Active ingredient

Phytosphingosine

Phytosphingosine

A skin lipid component used to support barrier structure and skin comfort.

Moderate evidenceStrongly supportive

Active ingredient

Pinus Pinaster Bark Extract

Pine Bark Extract

Pine bark extract, a polyphenol-rich antioxidant ingredient.

Moderate evidenceBarrier supportive

Humectant

Polyglucuronic Acid

Polyglucuronic Acid

A polysaccharide ingredient used to support hydration and skin conditioning.

Limited evidenceBarrier supportive

Humectant

Polyglutamic Acid

Polyglutamic Acid

A water-binding polymer that helps create a hydrated, cushioned skin feel.

Strong evidenceStrongly supportive

Emulsifier

Polyglyceryl-3 Methylglucose Distearate

Polyglyceryl-3 Methylglucose Distearate

A mild emulsifier used to create elegant, skin-comforting textures.

Functional evidenceCompatible

Emulsifier

Polysorbate 20

Polysorbate 20

A solubilizer used to disperse fragrance, oils, or actives in water-based systems.

Functional evidenceCompatible

Emulsifier

Polysorbate 60

Polysorbate 60

An emulsifier used to help stabilize cream and lotion textures.

Functional evidenceCompatible

Emulsifier

Polysorbate 80

Polysorbate 80

A solubilizer and emulsifier used to support formula uniformity.

Functional evidenceCompatible

Supportive

Portulaca Oleracea Extract

Purslane Extract

Purslane extract used in formulas for visible calm and skin comfort.

Limited evidenceBarrier supportive

Active ingredient

Potassium Azeloyl Diglycinate

Azeloglycine

An azelaic acid derivative used for tone, clarity, and oil-balance support.

Moderate evidenceBarrier supportive

Preservative

Potassium Sorbate

Potassium Sorbate

A preservative used to help protect formulas from microbial growth.

Strong evidenceCompatible

Supportive

Proline

Proline

An amino acid used in formulas designed for hydration and skin support.

Limited evidenceBarrier supportive

Humectant

Propanediol

Propanediol

A plant-derived solvent and humectant that supports softness and formula feel.

Moderate evidenceBarrier supportive

Active ingredient

Propolis Extract

Propolis Extract

A resinous bee-derived extract used in conditioning and clarity-focused formulas.

Moderate evidenceUse With Care

Humectant

Propylene Glycol

Propylene Glycol

A humectant and solvent used to support ingredient delivery and hydration.

Strong evidenceCompatible

Supportive

Propylene Glycol Alginate

Propylene Glycol Alginate

An alginate-derived thickener that supports viscosity and texture stability.

Functional evidenceCompatible

Emollient

Prunus Amygdalus Dulcis Oil

Sweet Almond Oil

Sweet almond oil, an emollient used to soften and condition dry skin.

Limited evidenceBarrier supportive

Emollient

Prunus Armeniaca Kernel Oil

Apricot Kernel Oil

Apricot kernel oil, a lightweight emollient used for softness and comfort.

Limited evidenceBarrier supportive

Supportive

Pseudoalteromonas Ferment Extract

Pseudoalteromonas Ferment Extract

A marine ferment extract used in formulas for hydration and skin comfort.

Limited evidenceBarrier supportive

Supportive

Pullulan

Pullulan

A polysaccharide film former that gives skin a smoother, softly tightened feel.

Functional evidenceCompatible

Active ingredient

Punica Granatum Fruit Extract

Pomegranate Extract

Pomegranate extract used for antioxidant and skin-conditioning support.

Limited evidenceBarrier supportive

Active ingredient

Quercetin

Quercetin

A flavonoid antioxidant used to support skin against visible environmental stress.

Limited evidenceBarrier supportive

Active ingredient

Resveratrol

Resveratrol

A polyphenol antioxidant used to support skin against visible environmental stress.

Moderate evidenceBarrier supportive

Active ingredient

Retinal

Retinal

A vitamin A derivative that supports visible renewal while requiring thoughtful barrier support.

Strong evidenceUse With Care

active

Retinaldehyde

Retinal

Retinaldehyde is an active skincare ingredient used to support visible renewal and smoother-looking skin as a potent retinoid option. It is especially relevant for fine lines, texture, and uneven tone.

Strong evidenceBarrier caution

Active ingredient

Retinol

Retinol

A vitamin A derivative that supports renewal, texture, and visible aging, best introduced gradually.

Strong evidenceUse With Care

Emollient

Rosa Canina Fruit Oil

Rosehip Oil

Rosehip oil, a botanical oil used for conditioning and skin softness.

Limited evidenceBarrier supportive

Emollient

Rubus Idaeus Seed Oil

Raspberry Seed Oil

Raspberry seed oil, a botanical lipid used for softness and conditioning.

Limited evidenceBarrier supportive

Active ingredient

Rumex Occidentalis Extract

Rumex Extract

Rumex extract used to support visible brightness and tone evenness.

Limited evidenceCompatible

Active ingredient

Rutin

Rutin

A flavonoid antioxidant used to support skin conditioning and visible calm.

Limited evidenceBarrier supportive

Humectant

Saccharide Isomerate

Saccharide Isomerate

A carbohydrate complex used for long-lasting moisture binding.

Moderate evidenceStrongly supportive